What Is Cyclopia, the Cause of One-Eyed Baby?

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The condition of one-eyed babies born in Mandiling Natal Regency, North Sumatra, Thursday, September 13, 2018, is very concerning. He was born with only one eye in the middle, also without a nose. The female baby was born at Panayabung Regional General Hospital at 15.25 WIB, and died seven afterwards.

The head of the Mandailing Natal District Health Office, Syarifuddin Nasution, said many factors could cause the baby to experience such conditions. Including, one of them, is exposure to mercury, viruses, or drugs.


"If it is associated with the work of the baby's father as a miner, it could be. We are still having trouble getting information because his family is still closed," Syarifuddin said, as quoted by Antara.

In the world of health, the condition is known as cyclopia or alobar holoprosencephaly. According to Healthline.com, this case includes the rarest birth defects in the world. Comparison of 1: 100,000 newborn babies.

Cyclopia occurs because the radiation received by the fetus in the uterus. Exposure to this radiation affects the formation of the baby's eyes or other body organs that are not perfectly formed. This imperfect formation of eyes and nose is because the forebrain does not divide perfectly.

Usually, cyclopia also causes miscarriage or short-term babies. The problem is that the baby or fetus with this condition will be followed by other health problems, such as a baby's brain malformation.

Although often associated with radiation exposure, the exact cause of cyclopia is uncertain. There are several studies which reveal that chemical radiation exposure is not directly correlated with cyclopia.

There is also research that mentions that the cause is chromosomal abnormalities. Cyclopia or alobar holoprosencephaly can occur because there are three copies of chromosome 13 (trisomy). This disorder, which is often called patau syndrome, causes unbalanced development of the otate, heart, kidneys, lips, and oral cavity.

However, other chromosomal abnormalities, chromosome 18 for example, are also often found to cause cyclopia.

One thing is certain, cyclopia can be detected from the womb using ultrasound. Disability in the womb occurs in the third and fourth weeks of pregnancy.

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